Our Clinical Trials
ECU Exercise Medicine Research Institute
Clinical Trials Open For Enrolment
Prostate cancer
This project aims to investigate whether physical exercise can improve the response to radiotherapy and enhance the effectiveness of treatment in people with prostate cancer.
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EMRI Clinical Trials
Prostate
Prostate
Recruiting
Eradicate
This project aims to investigate whether physical exercise can improve the response to radiotherapy and enhance the effectiveness of treatment in people with prostate cancer.
Prostate
Recruiting
Myex
The aim of this study is to examine the feasibility and efficacy of a supervised, multicomponent exercise program in patients with localised pancreatic cancer undergoing preoperative therapy.
Prostate
In Follow up
PC Essentials
Aim 1: Determine the effectiveness of a nurse-led survivorship care intervention (PCEssentials) relative to usual care, for improving health related quality of life in men with prostate cancer undergoing androgren deprivation therapy.
Aim 2: Evaluate PCEssentials implementation strategies and outcomes, including cost-effectiveness of PCEssentials, with respect to usual care, as well as acceptability, adoption, appropriateness, feasibility, fidelity, penetration and sustainability.
Prostate
Recruiting
Cytocomp
The aims of this study are 1) to compare blood factors (cytokines) influencing cancer growth in age-matched healthy individuals and patients with different stages of prostate cancer and treatment, 2) evaluate the association between cytokine levels and body composition (muscle mass and fat mass), 3) investigate the association between levels of cytokines and prostate cancer cell growth when exposed to collected blood samples.
Prostate
Recruiting
Eradicate Rex
This study aims to investigate whether physical exercise has the potential to improve the response to radiotherapy and enhance the effectiveness of treatment in people with prostate cancer.
Prostate
In Follow-up
Telex
This study aims to determine if an exercise program delivered via telehealth is as effective as the supervised clinic-based program for reduction in fat mass, increase in lean mass, reducing cardiovascular risk, and enhancing physical and mental health in men with prostate cancer.
Prostate
In Follow-up
Interval-MCRPC
The aim of this study is to determine if supervised high intensity aerobic resistance training increases overall survival compared to self-directed exercise in patients with metastatic prostate cancer.
Prostate
In Follow-up
Active Surveillance
The aim of this study is to determine the efficacy of implementing a program of exercise medicine specifically prescribed to delay (or prevent) transition to active therapies and to impede prostate cancer progression.
Prostate
Completed
Gut
This study aims to determine if an exercise medicine program can mediate gut microbiota and its metabolome in men with prostate cancer receiving androgen deprivation therapy.
Prostate
Completed
Creatine Prostate Cancer
This study aims to examine the effects of creatine supplementation in conjunction with resistance training on body composition, muscle strength and physical function in prostate cancer patients undergoing androgen deprivation therapy.
Prostate
Completed
Hypoxia
The aim of this study is to investigate whether exercise has the potential to enhance the effectiveness of treatment by increasing blood flow and thus ozygen supply to the tissue that is being irradiated. The study will assess patient safety and tolerance to an exercise program during treatment, its feasibility and potential effectiveness.
Prostate
Completed
TrueNTH
The key objective of this intervention is to develop and evaluate a personalised online resource together with a model of face-to-face service, a telehealth solution (for rural/remote men and their partners/carers), and additional support materials for targeted groups (Indigenous and culturally and linguistically diverse groups) with the goal of improving the healthy lifestyle attitudes, knowledge, behaviour, and confidence to underpin the achievement of prostate cancer survivorship programs.
Prostate
Completed
Sexual Health
The purpose of this study is to: 1) examine the efficacy of exercise as a therapy to aid in the management of sexual dysfunction in men with prostate cancer; 2) determine if combining exercise and brief psychosexual intervention results in more pronounced improvements in sexual health; and 3) assess if any benefit of exercise and psychsexual intervention on sexual dysfunction is sustained long term.
Prostate
Completed
Pre-Prostatectomy
This study will evaluate an exercise medicine intervention undertaken pre-surgery aimed at enhancing pre-surgical physical function, quality of life and improved post-surgical recovery.
Prostate
Completed
Prostate Spinal Mets
The aim of this study is to dermine the effiacy and safety of a modular multi-modal exercise program in prostate cancer patients with bone metastases.
Prostate
Completed
Bone Mets
The aim of this study is to determine the efficacy and safety of a modular multi-modal exercise program in prostate cancer patients with bone metastases.
Prostate
Completed
Lucrin ManPlan
The aim of this study was to investigate the effectiveness of an industry-led, treatment-integrated, community-based exercise program on outcomes of body weight, cardiovascular health, and physical function.
Prostate
Completed
Immediate AST
The aim of this project is to examine the beneficial effect of implementing exercise therapy at the onset of androgren suppression therapy (AST).
Prostate
Completed
Vibration Prostate
This study aims to examine the effect of vibration training on markers of bone health in prostate cancer survivors on androgen suppression therapy (AST).
Prostate
Completed
Lucrin
The purpose of this study is to determine if immediate exercise therapy can improve patient health by reducing initial adverse effects during the initial phase of Lucrin treatment and if this provides superior benefits to delayed exercise therapy.
Prostate
Completed
Ex Med for all Cancer Survivors
The purpose of this study is to investigate the impact of exercise on the health and wellbeing of cancer survivors.
Prostate
Completed
ADT Exercise Modes
The purpose of this investigation is to examine the effects of long term exercise on reversing musculoskeletal-related side effects, and cardiovascula and diabetes risk factors in men receiving androgen deprivation for their prostate cancer.
Prostate
Completed
Radar
The purpose of this study is to determine the effects, efficacy, retention and compliance of a physical exercise intervention in a large established cohor of prostate cancer patients from the Randomised Androgen Deprivation and Radiotherapy (RADAR) study.
Prostate
Completed
Bone Mets Pilot
The aim of this trial was to determine the safety and efficacy of resistance exercise by prostate cancer survivors with bone metastatic disease.
Prostate
Completed
Weight Loss Prostate
Patient population: men with prostate cancer receiving ADT for a minimum of 6 months, anticipated to remain on ADT for the entire study period, and being obese, defined as a body fat percentage ≥25%.
Prostate
Completed
Weight Loss Prostatectomy
This study examined the efficacy of a weight loss program for altering body composition in prostate cancer patients prior to robot assisted radical prostatectomy (RARP).
Prostate
Completed
Combined resistance aerobic ADT
Reverses Muscle Loss in Men Undergoing Androgen Suppression Therapy for Prostate Cancer Without Bone Metastases: A Randomized Controlled Trial.
Prostate
Completed
Resistance exercise ADT
Resistance exercise in men receiving androgen depriving therapy for prostate cancer.
Brain
Completed
Exercise Glioblastoma
The aim of this study was to evaluate the feasibility and preliminary efficacy of supervised exercise incorporating autoregulation in patients with Glioblastoma.
Neuro
Completed
Neuromuscular Electrical Stimulation in Spinal Cord Injury
The aim of the present study was to investigate the effects of high-intensity strength training performed under isometric conditions using low- to moderate-frequency (30 Hz) NMES
Breast
Breast
Completed
Breast Spinal Mets
This study aims to examine the effects of creatine supplementation in conjunction with resistance training on body composition, muscle strength and physical function in prostate cancer patients undergoing androgen deprivation therapy.
Breast
Completed
Vibration Breast
The aim of this study is to examine the effect of vibration training on bone health in breast cancer patients who are prescribed aromatase inhibitors.
Breast
Completed
Lymphoedema
The purpose of this study is to determine the strength of effect of high versus low intensity upper body resistance exercise on lymphoedema status and symptoms, physical function and quality of life in breast cancer related lymphoedema (BCRL) patients.
Breast
Completed
Breast Cancer Radiation
The aim of this study is to examine the feasibility and efficacy of a 12 week home based resistance and aerobic exercise program on cancer related fatigue in breast cancer patients during and after radical radiation therapy.
Breast
Completed
Breast Myokine
Acute and Chronic Exercise Effects on Myokine Levels and Cancer Cell Suppression in Survivors of Breast Cancer: a randomized trial.
Pancreatic
Pancreatic
Recruiting
EXPAN
The aim of this study is to examine the feasibility and efficacy of a supervised, multicomponent exercise program in patients with localised pancreatic cancer undergoing preoperative therapy.
Bladder
Bladder
Completed
Exercyst
The aim of this study is to improve the functional status of patients prior to radical cystectomy and improve patient outcomes following surgery.
Endometrial
Endometrial
In Follow Up
Endo
The aim of this study is to assess the feasibility of a combined exercise and nutrition prehabilitation program for patients with endometrial cancer scheduled for surgery.
Lung
Lung
Recruiting
ISC-TEAM
This study looks at whether an integrated supportive care program including counselling to provide individualised care plans for nutrition, physical activity, and psychological well-being can improve physical activity levels in people with MPE.
Lung
Completed
Exercise Adoption
The purpose of this research is to investigate the effects of a short-term exercise program designed to improve physical functioning and facilitate long-term adoption of exercise.
Lung
In Follow Up
Muscle Mass in Mesothelioma
The overall aim of this research is to examine the relationship between skeletal muscle and important clinical outcomes in patients with malignant pleural mesothelioma (MPM)
Lung
Completed
INTERMix
Following a diagnosis of mesothelioma there can be declines in health and wellbeing. Many people experience weight loss, poor appetite, tiredness, shortness of breath, and pain.
Lung
Completed
Activity Behaviours in Mesothelioma
Following a diagnosis of malignant pleural effusion there can be declines in health and wellbeing. One purpose of this research is to find out how much activity you do, and how much time you spend sitting or lying down.
Colorectal
Colorectal
Completed
Pre Rectal Resection
The purpose of this study is to determine the feasibility and potential effectiveness of a supervised presurgical exercise program consisting of combined resistance and aerobic training in patients with rectal cancer scheduled to receive rectal resection.
Brain
Brain
Completed
Exercise Glioblastoma
The aim of this study was to evaluate the feasibility and preliminary efficacy of supervised exercise incorporating autoregulation in patients with Glioblastoma.
Neuro
Neuro
Completed
Neuromuscular Electrical Stimulation in Spinal Cord Injury
The aim of the present study was to investigate the effects of high-intensity strength training performed under isometric conditions using low- to moderate-frequency (30 Hz) NMES
Children
Children
Completed
Resistance exercise children
The purpose of this study is to investigate the effect of an 8-week resistance training program on children who were overweight or obese.
Children
Completed
Exercise in childhood cancer survivors
The purpose of this study is to investigate the effect of exercise training program on children who were overweight or obese.
Healthy Ageing
Healthy Ageing
Completed
Wicking Ageing Study
The aim of this study is to investigate the effects of resistance and aerobic exercise on physical function, body composition and memory in healthy older adults.
Healthy Ageing
Completed
Vexmed
The objectives of this study are:
1. Determine the barriers, facilitators, safety, acceptance and efficacy of the telehealth programs implemented by ECU during the COVID-19 self-isolation.
2. Evaluate impact of the pandemic on physical fitness, cognitive function and mental health of older adults who participated in a face to face ECU community exercise program called “Stay Sharp”.
Depression
Depression
Completed
ACTIVEDEP
The aim of this study is to evaluate the efficacy of a home-based exercise programme added to usual medical care for the treatment of depression.
Melanoma
Melanoma
Completed
Exercise Melanoma
To determine the feasibility, safety and preliminary efficacy of a telehealth supervised exercise programme in patients with advanced melanoma receiving checkpoint inhibitor therapy
Other
All Cancers
Completed
Life Now Exercise
The purpose of this study is to investigate the impact of exercise on the health and wellbeing of cancer survivors.
All Cancers
Completed
Exercise within a Cancer Centre
The aim of this study was to evaluate the safety, effectiveness, and acceptability of an exercise clinic co-located within a cancer treatment centre to identify best practices for integrating exercise medicine into cancer care.
